ahajournals.org6d
Muscle Mass and Glucagon-Like Peptide-1 Receptor Agonists: Adaptive or Maladaptive Response to Weight Loss?
Recent studies have shown that pharmacologic weight loss with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and ...
ahajournals.org6d
Cardiac Arrhythmias and Autonomic Dysfunction Associated With COVID-19: A Scientific Statement From the American Heart Association
Cardiac arrhythmias are commonly noted in patients during infections with and recovery from COVID-19. Arrhythmic manifestations span the spectrum of innocuous and benign to life-threatening and deadly ...
ahajournals.org6d
Patients With Advanced Heart Failure and Atrial Fibrillation Deserve an Attempt at Catheter Ablation as First-Line Therapy
Brachmann J, Sohns C, Andresen D, Siebels J, Sehner S, Boersma L, Merkely B, Pokushalov E, Sanders P, Schunkert H, et al.
ahajournals.org5d
YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division
BACKGROUND: Many specialized cells in adult organs acquire a state of cell cycle arrest and quiescence through unknown ...
ahajournals.org5d
A Rare Noncoding Enhancer Variant in SCN5A Contributes to the High Prevalence of Brugada Syndrome in Thailand
BACKGROUND: Brugada syndrome (BrS) is a cardiac arrhythmia disorder that causes sudden death in young adults. Rare genetic ...
ahajournals.org9d
Challenges and Opportunities in Aortic Dissection: The Journey to Personalized Medicine
The surgical principles for acute type A AD are (1) eliminate the entry tear, (2) restore coronary flow and aortic valve ...
ahajournals.org6d
Pathogenesis of Atherothrombotic Events: From Lumen to Lesion and Beyond
Our concepts of the pathogenesis of acute coronary syndromes have evolved considerably over time. Our concepts about the acute coronary syndromes have evolved markedly since the founding of the ...
ahajournals.org4d
Cardiopulmonary Fitness and Personalized Exercise Prescription in Patients With Hypertrophic Cardiomyopathy
Patients with hypertrophic cardiomyopathy (HCM) are generally restricted regarding participation in competitive sports based on the potential risk of sudden cardiac death and malignant arrhythmias. As ...
ahajournals.org17d
Predicting Individual Treatment Effects to Determine Duration of Dual Antiplatelet Therapy After Stent Implantation
After coronary stent implantation, prolonged dual antiplatelet therapy (DAPT) increases bleeding risk, requiring personalization of DAPT duration. The aim of this study was to develop and validate a ...
ahajournals.org6d
Journal of the American Heart Association
In the past decade, the biological functions of various RNA modifications in mammals have been uncovered. N4‐acetylcytidine (ac4C), a highly conserved RNA modification, has been implicated in human ...
ahajournals.org6d
Third‐Trimester Cardiovascular Function and Risk of Hypertensive Disorders of Pregnancy
Whether cardiovascular dysfunction is associated with preeclampsia in women without fetal growth restriction (FGR) is unclear. Our objective was to investigate associations between third‐trimester ...
ahajournals.org6d
Statin Therapy Reduces Radiation‐Induced Cardiotoxicity in Patients With Breast Cancer Receiving Adjuvant Radiotherapy
To evaluate the efficacy of statin therapy in reducing major adverse cardiovascular event (MACE) risk among patients with breast cancer undergoing breast‐conserving surgery and adjuvant whole breast ...