Every year, more than 5 million people in the U.S. are diagnosed with heart valve disease, but this condition has no ...

In the Nature Communications study, inhibiting RSK1 helped reverse the progression of MPNs in mice, reducing fibrosis, or scar formation, in the bone marrow. Inhibiting RSK1 eliminated up to 96% ...

This paper first explores the design strategies and mechanisms of nanozyme-based targeted therapy, then introduces its application in key CVDs, such as ischemic stroke, myocardial infarction, and ...

Given changes in patient characteristics and treatments over time, a contemporary risk model for patients with acute myocardial infarction (MI) is needed. Data from 313 825 acute MI hospitalizations ...

Introduction: Interleukin-10 (IL-10) is a potent immunomodulatory cytokine widely explored as a therapeutic agent for diseases, including myocardial infarction (MI ... of the entire left ventricular ...

On the basis of our observations, we reviewed the available literature concerning scar or fibrous tissue production as influenced by angiotensin-converting enzyme, angiotensin II (an important ...