Background Colorectal cancer (CRC) is a common and preventable disease for which screening rates by colonoscopy remain unacceptably low. Our primary objective was to develop and validate a clinical ...

Background Mounting epidemiological evidence supports a role for phosphatase and tensin homologue (PTEN)-T cell leukaemia 1 (Tcl1) signalling deregulation in hepatocarcinogenesis. Objective To ...

2 Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 3 Translational Research Center for Gastrointestinal ...

Correspondence to Dr Citadel J Cabasag, Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France; cabasagc{at}fellows.iarc.fr We read with interest the commentary by ...

Correspondence to Dr Feng Sun, Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100191, China; sunfeng{at}bjmu.edu.cn SS and QY contributed equally.

2 Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Tianjin, China Objective Hepatitis B virus (HBV ...

Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...

1 State Key Laboratory of Systems Medicine for Cancer, Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Centre ...

Objective To examine the effectiveness of green-Mediterranean (MED) diet, further restricted in red/processed meat, and enriched with green plants and polyphenols on non-alcoholic fatty liver disease ...

University of Technology of Compiègne, UMR CNRS 6600 – Biomechanics and Bioengineering, Compiègne, France Correspondence to Dr C Legallais, UTC, UMR CNRS 6600 Biomechanics and Bioengineering, BP 20529 ...

Endoscopic sphincterotomy to prevent post-ERCP pancreatitis after self-expandable metal stent placement for distal malignant biliary obstruction (SPHINX): a multicentre, randomised controlled trial ...

Objective Over half of patients with IBS have either diarrhoea (IBS-D) or a mixed stool pattern (IBS-M). The relative efficacy of licenced pharmacological therapies is unclear in the absence of ...