While this scar is essential for holding the heart together, it cannot contract like healthy heart muscle. Over time, this non-contractile scar tissue can reduce how well the heart pumps blood.

Late gadolinium enhancement MRI (LGE MRI) is the gold standard for the detection of myocardial scars post myocardial infarction (MI). LGE MRI requires the injection of a contrast agent, which carries ...

Previous studies, the investigators continued, “… suggest a role for GPNMB in regulating post-infarction outcomes but the mechanisms of GPNMB effects on the infarcted heart remain unclear.

Myocardial ischemia is a drop in blood flow to the heart. Myocardial infarction, or heart attack, occurs when death or damage occurs in the muscle tissue of the heart due to low blood supply.

“The results of our study point to a possible new target to reverse scarring after myocardial infarction, which has never been shown before.” Scar Tissue Challenges in Mammals A myocardial infarction ...

A myocardial infarction causes the death of massive numbers of heart cells. To repair the injury, the body replaces the damaged and dead cells with scar tissue.

A myocardial infarction causes the death of massive numbers of heart cells. To repair the injury, the body replaces the damaged and dead cells with scar tissue.

Coronary artery disease is the leading cause of heart failure (HF). 1 After myocardial infarction (MI), an intense inflammatory reaction is activated to remove dead cells and activate the replacement ...