The Fighting Irish have played two opponents more than once without posting a victory, including the Bulldogs.

The final quarterfinal matchup of the 2024-25 College Football Playoff features two of the most iconic programs in college football history, as SEC champion (2) Georgia takes on (7) Notre Dame in the Sugar Bowl.

The stakes won't be quite as high on Wednesday night when No. 2 Georgia (11-2, CFP No. 2 seed) and No. 3 Notre Dame (11-1, CFP No. 5 seed) meet in the same storied bowl, but it's still pretty big.

Notre Dame has the chance to record its biggest win in over 30 years against Georgia in the Sugar Bowl. The question is: will it?

The second round of the NCAA FBS college football playoffs conclude Wednesday with No. 7 Notre Dame vs. No. 2 Georgia in a Sugar Bowl quarterfinal

One hero of Georgia’s previous Sugar Bowl appearance against Notre Dame hopes so. Then Bulldogs safety Scott Woerner had two interceptions on New Year’s Day, 1981, the last one helping to clinch a 17-10 victory and the national championship.

Wednesday, 8:45 p.m. EST (ESPN) BetMGM College Football Odds: Georgia by 1 1/2. Series record: Georgia leads 3-0. What’s at stake? The winner moves on to a College Football Playoff semifinal at the Orange Bowl in the first year of the expanded 12-team format.

CBS Sports college football analyst Josh Pate has built himself into one of the true voices of college football through his analysis and overall knowledge of the game. On top of being entertaining to watch and listen to, Pate is fair to all conferences/teams and does his best to not have any sort of personal bias.

History will not be on Notre Dame’s side when it faces Georgia in the College Football Playoff quarterfinals at the Sugar Bowl tonight.

Get the latest Notre Dame vs. Georgia predictions ahead of their college football playoff quarterfinal clash. Free Sugar Bowl picks and predictions for January 1.