Department of Life Science Informatics and Data Science, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, ...
MEK mitogen-activated protein kinase kinase, MT mutant, Pi inorganic phosphate, P13K phosphoinositide 3-kinase, PLCε phospholipase Cε, RALGDS Ral guanine nucleotide dissociation stimulator ...
Eli Lilly (LLY) agreed to acquire an experimental treatment for breast cancer and other advanced solid tumors from Scorpion Therapeutics for up to $2.5 billion. The purchase price includes an upfront ...
In a report released today, Graig Suvannavejh from Mizuho Securities reiterated a Buy rating on Verastem (VSTM – Research Report), with a price ...
In some cases, the ketogenic diet made the anticancer drugs phosphoinositide 3-kinase inhibitors (PI3K inhibitors) work more effectively. This effect was partly attributed to the fact that the ...
For example, mutations in proteins of the PI3K–mTOR (phosphoinositide 3-kinase–mammalian target of rapamycin) pathway — which is commonly activated in cancer — have been shown to drive ...
Such pathways included those that were related to hypoxia, including PTEN (phosphatase and tensin homolog), PI3K (phosphoinositide 3-kinase), and MAPK (mitogen-activated protein kinase) signaling. WNT ...
Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Laboratory, College of Biotechnology Tianjin University of Science and Technology, Tianjin ...
An enzyme that helps clear damaged mitochondria can act as a molecular switch and potentially prevent neurons from dying.