Nov 12, 2024 · Semaglutide weight loss brand is Wegovy is the only semaglutide brand that is FDA brand approved for weight loss. Semaglutide injections (Ozempic and Wegovy) are given as subcutaneous injections once a week. Rybelsus is a tablet that you take once a day in the morning, 30 minutes before eating, drinking, or taking any other medicines.